Cholinergic Synapses are found everywhere within our central nervous system.  Due to their presence in high amounts within the thalamus, striatum, limbic system, and neocortex,  it is likely they are important for memory, learning, attention and other higher brain functions, and may even serve a valuable role in brain homeostasis. (1)  Some medical practitioners have turned to the potential uses of Cholinergic Synapses for the use in an anti-inflammatory treatments.  It is believed that due to the overlap of the nervous and immune systems this may lead to “explosive growth in our understanding of neuroanatomical, cellular, and molecular mechanisms that mediate central modulation of immune functions through the autonomic nervous system.” (2)  These discoveries has already lead to research into the efficacy of its use in the treatment of human inflammatory diseases.

Many people take supplements to boost their Cholinergic Synapses.  They purchase over-the-counter products called cholinergics for this purpose.

What are cholinergics?  To describe it as simply as possible, it refers to any substance that encourages greater acetylcholine levels.  Choline, often purchased as choline bitartrate is an example of a cholinergic, others include Alpha GPC,  or Huperzine A.  Some compounds reduce the synthesis of acetylcholinesterase, the enzyme responsible for the breakdown of acetylcholine, others promote its production.  No matter the mechanism used, the goal of a cholinergic is to help make acetylcholine more abundant in the central nervous system.

Why would someone want to increase the available Acetylcholine in their brain?

Acetylcholine is a neurotransmitter essential for proper function within the peripheral and central nervous systems.  In the brain, it is strongly linked with the effectiveness of our short term memory, motivation, mood, and attention.  Essentially it helps us ensure our operating system is running fast and processing every bit of data correctly.  Sometimes we feel like our brain power isn’t enough to complete the complex tasks of our lives or keep up with the hardships we are forced to face.  Many find that by increasing their available Acetylcholine levels help them live more productive, higher quality lives.  This is where cholinergics come in, with compounds like CDP Choline or Alpha GPC they use these supplements to optimize their cognitive performance with higher neurotransmitter availability.

Cholinergic Synapses are found everywhere within our central nervous system.  Scientists believe that due to their presence in high amounts within the thalamus, striatum, limbic system, and neocortex,  it is likely they are important for memory, learning, attention and other higher brain functions, and may even serve a valuable role in brain homeostasis. (3)

This article is not a replacement for medical care.  Consult your doctor before making any changes to your wellness routine.